Paper Type |
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Research Paper |
Title |
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Effect of Nitrite Toxicity on Histological Parameters to Fresh Water Fish "Cirrhinus Mrigala" |
Country |
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India |
Authors |
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Yesudass Thangam |
Page No. |
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16-21 |
 |
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10.9790/3021-04631621  |
 |
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0.4/3021-04631621 .png) |
 |
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3021-0406-0321  |
Nitrite compound exerts environmental stress on fish. High levels of nitrite in water results in high stress levels leading to hyperventilation, elevated heart rate, increased blood pressure in fish. The present study was to evaluate the histopathological changes in liver exposed to nitrite toxicity during 7th, 14th, 21st , 28th , and 35th , days respectively. Morphological structure of liver of Cirrhinus mrigala was presented in (Ph. m. 8). In the control fish, the liver showed hepatic cells located with central nucleus and homogenous cytoplasm. During acute treatment the liver exhibit disintegration of parenchymal cells, extensive vacuolation of parenchymal hepatocytes, degenerative cell and organelles and lumen with necrotic cells (Ph. m. 9). During sublethal treatment liver showed enlargements of hepatocytes, disintegration of cell boundaries of intercellular spaces, nuclear degeneration with pyknotic nucleus were noticed at the end of 7th day (Ph. m. 10). At the end of 14th day, disintegration of hepatocytes and necrosis of parenchymatous tissue noticed. The cell undergo necrosis or apoptosis. It is followed by karyorrhexis or fragmentation of the nucleus (Ph. m. 11). The above said structural changes were severe at the end of 21st and 28th , exposure period (Ph. m. 12, 13). Complete rupture of hepatic cells, vacuolar degeneration, intercellular edema, were observed at the end of the treatment period (Ph. m. 14).
Keywords: - Cirrhinus mrigala, Nitrite, Fish liver
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